Alcanza Clinical Research

AstraZeneca has initiated the Solstice study, a global Phase 2 clinical trial evaluating an investigational type 2 diabetes medication in adults.

You may be eligible to participate in this study if you:

• Are at least 18 years old
• Have been diagnosed with type 2 diabetes for at least 6 months
• Are managing your diabetes with diet and exercise alone, or in combination with metformin or a SGLT2 inhibitor medication.
• Have an HbAlc between 7% and 10.5%, inclusive. Have a BMI of 23 or higher
• Have not taken any weight loss medications in the past 3 months
• Have not had, and are not planning to have bariatric surgery or fitting of a weight loss device
• Do not have type 1 diabetes

Additional criteria will be assessed to confirm eligibility.

When you eat, your body releases a hormone called GLP-1 that signals a feeling of fullness, slows gastric (stomach) emptying, and lowers blood sugar levels. The investigational drug, AZD5004, has been designed to work like GLP-1 to help lower blood sugar levels and promote weight loss.

People in the Solstice study will take either AZD5004, an approved oral diabetes medication called semaglutide, or placebo tablets once a day for up to 26 weeks (approximately 6 months). There is a higher chance of receiving AZD5004 or semaglutide than of receiving placebo if you participate in the study.

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Study Locations

Charlottesville Medical Research

325 Winding River Lane
Charlottesville, Virginia 22911

+1 (434) 817-2442

Quest Research Institute

28555 Orchard Lake Road
Farmington Hills, Michigan 48334

+1 (248) 957-8940

Boston Clinical Trials

26 Cummins Highway
Boston, Massachusetts 02131

(617) 477-4868

Accel Research – Birmingham

2017 Canyon Road
Vestavia Hills, Alabama 35516

+1 (205) 757-8301

Accel Research – St. Petersburg-Largo

8250 Bryan Dairy Rd
Largo, Florida 33777

(727) 347-8839